منابع مشابه
Environmental exposure to carcinogens in northwestern Cameroon.
BACKGROUND In developing countries, 6% of deaths are due to cancer but cancer prevention is not practiced. Humans can prevent themselves from a number of workplace and environmental carcinogens. OBJECTIVES To assess exposure to carcinogens, risky behaviours and associated preventive methods. METHODS A structured questionnaire was used to collect information on carcinogen exposure in the wor...
متن کاملAllergic contact sensitizing chemicals as environmental carcinogens.
Chemicals that were bioassayed by the National Toxicology Program (NTP) and that also produce allergic dermatitis (ACD) in humans were evaluated for their tumorigenic characteristics. The impetus for the study was that most contact sensitizers, i.e., those that produce ACD, and genotoxic carcinogens are chemically similar in that they are electrophilic, thereby producing adducts on macromolecul...
متن کاملChildren and increased susceptibility to environmental carcinogens: evidence or empathy?
Introduction The WHO Task Force for the Protection of Children’s Environmental Health declared in its Bangkok statement that “children are not little adults.” The premise behind this principle is that children have an exceptional vulnerability to both the acute and chronic effects of environmental hazards and that they are disproportionately susceptible by comparison with adults. Indeed, the Ba...
متن کاملInternational Commission for Protection against Environmental Mutagens and Carcinogens (ICPEMC)
The International Commission for Protection against Environmental Mutagens and Carcinogens (ICPEMC) was founded (1-8) in January of 1977 as a result of a meeting organized by the Institut de la Vie in June of 1976. ICPEMC is sponsored by the Institut de la Vie, and is affiliated with the International Association of Environmental Mutagen Societies. During its first year the Commission establish...
متن کاملp 53 mutations as fingerprints of environmental carcinogens *
Mutations of the p53 tumor suppressor gene occur in a great majority of human cancers. The protein product of p53 gene is involved in DNA damage response. Consequently, p53 gene may be a preferred target for environmental carcinogens, which also act as DNAdamaging agents. This is probably why p53 mutations are frequent in cancers linked to environmental carcinogens. Moreover, these carcinogens ...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1969
ISSN: 0035-9157
DOI: 10.1177/003591576906201035